Review of intravenous immunoglobulin replacement therapy trials for primary humoral immunodeficiency patients
| Autor: | Harry W. Schroeder, Christopher J. Dougherty |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Alternative medicine MEDLINE Review Pharmacokinetics hemic and lymphatic diseases medicine Humans Intensive care medicine Immunodeficiency Intravenous immunoglobulin Licensure IVIG Clinical Trials as Topic Primary immunodeficiency biology business.industry PID Immunologic Deficiency Syndromes Immunoglobulins Intravenous General Medicine medicine.disease Clinical trial Infectious Diseases Immunology Practice Guidelines as Topic biology.protein Antibody business |
| Zdroj: | Infection |
| ISSN: | 1439-0973 |
| Popis: | An available supply of intravenous immunoglobulin (IVIG) is essential for individuals with primary humoral immunodeficiency. A shortage in 1997 prompted the Food and Drug Administration (FDA) to revise guidelines for the licensure, production, and distribution of new IVIG products, including the standardization of United States clinical trials regarding endpoints for safety, efficacy, and pharmacokinetics. The following review is intended to present current information and results of clinical trials in patients with primary immunodeficiency treated with IVIG products currently licensed or awaiting licensure in the United States. The data presented are compiled from published clinical trials and prescribing information generated by manufacturers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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