Changes in latent fingermark glyceride composition as a function of sample age using UPLC-IMS-QToF-MSE
| Autor: | Natalie Kummer, Amanda A. Frick, Céline Weyermann, Ana Moraleda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Time Factors Lipid fraction Glyceride Carboxylic acid F400 F100 Mass spectrometry 01 natural sciences Biochemistry High-performance liquid chromatography Mass Spectrometry Analytical Chemistry Diglycerides 03 medical and health sciences 0302 clinical medicine Ozone Electrochemistry Environmental Chemistry Humans Spectroscopy 030216 legal & forensic medicine Dermatoglyphics Chromatography High Pressure Liquid Triglycerides chemistry.chemical_classification Ozonolysis Chromatography 010401 analytical chemistry C100 0104 chemical sciences chemistry Fatty Acids Unsaturated Oxidation-Reduction |
| Zdroj: | The Analyst, vol. 145, no. 12, pp. 4212-4223 |
| ISSN: | 0003-2654 |
| Popis: | The composition of fingermark residue has been an important topic in forensic science, mainly in efforts to better understand and eventually improve the efficacy of latent fingermark detection methods. While the lipid fraction has been extensively studied, there is currently little information about how the glyceride fraction of latent fingermarks is chemically altered over time following deposition. A previously reported untargeted ultra performance liquid chromatography-ion mobility spectrometry-quadrupole time-of-flight mass spectrometry (UPLC-IMS-QToF-MSE) method was used to investigate changes over time in fingermark di- and triglycerides. Charged latent fingermark samples from 5 donors were analysed up to 28 days following deposition. Significant changes in glyceride composition occurred with increased sample age, attributed primarily to the oxidation of unsaturated triglycerides through ozonolysis. Considerably fewer unsaturated TGs were identified in samples 7 and 28 days following deposition, while mono- and diozonides of these lipids were identified as major components of aged samples. Additional compounds were identified as possible aldehyde and carboxylic acid derivatives resulting from the reaction of water with ozonolysis intermediates. While the onset of these processes occurred rapidly following deposition, continuing oxidation over time was seen via the progressive ozonolysis of diunsaturated triglycerides. These results represent a further step towards understanding the factors affecting fingermark composition, ageing and subsequent detection under operational conditions. |
| Databáze: | OpenAIRE |
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