Predictors of Pneumocystosis or Tuberculosis in HIV-Infected Asian Patients With AFB Smear-Negative Sputum Pneumonia
| Autor: | Borann Sar, Nguyen Hong Duc, Manil Saman, Nguyen Huu Lan, Muriel Vray, Loïc Chartier, Yves Germani, Odile Le Minor, Sarin Chan, Nguyen Thi Phuong Lan, Pierre L'Her, Didier Laureillard, Arnaud Fontanet, Charles Mayaud |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis HIV Infections Cohort Studies Predictive Value of Tests Internal medicine Pneumocystosis Humans Medicine Pharmacology (medical) Tuberculosis Pulmonary AIDS-Related Opportunistic Infections business.industry Pneumonia Pneumocystis Respiratory disease Sputum Odds ratio medicine.disease Confidence interval Pneumonia Logistic Models Infectious Diseases Vietnam Immunology Female medicine.symptom Cambodia business Cohort study |
| Zdroj: | JAIDS Journal of Acquired Immune Deficiency Syndromes. 48:620-627 |
| ISSN: | 1525-4135 |
| Popis: | Objectives: To identify predictors of Pneumocystis jiroveci pneumonia (PCP) or pulmonary tuberculosis (TB) in acid-fast bacillus smear-negative HIV-infected patients and to develop clinical prediction rules. Design: A cohort study conducted in consecutive hospitalized Asian patients. Methods: Multivariate analyses were performed on the Cambodian sample to determine clinical, radiological, and biological predictors of PCP or TB at hospital admission. The Vietnamese sample was kept for independent validation. Results: In Cambodia, the gold standard technique for TB and PCP were fulfilled in 172 (27 cases) and 160 (84 cases) patients, respectively. For TB, independent predictors included the following: headache [odds ratio (OR) 3.0; 95% confidence interval (CI) 1.04 to 8.6], localized radiological opacity (OR 5.8; 95% Cl 1.9-17.9), and mediastinal adenopathy (OR 10.1; 95% CI 3.5 to 29.0); and for PCP: resting oxygen saturation |
| Databáze: | OpenAIRE |
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