Interaction between low level laser therapy and anesthesia in wistar rats
| Autor: | Anamaria Meireles, Thiago Fernando Mattjie, Gladson Ricardo Flor Bertolini, Lígia Inez Silva, Bruno Pogorzelski Rocha, Tatiane Kamada Errero |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Medicine (General)
business.industry medicine.medical_treatment Intraperitoneal injection Ketamine hydrochloride General Medicine Hindlimb anesthesia Body weight pain measurement General Biochemistry Genetics and Molecular Biology Xylazine RS1-441 low-level laser therapy Nociception R5-920 Pharmacy and materia medica Grip Strength Test Anesthesia medicine business Low level laser therapy medicine.drug |
| Zdroj: | Acta Scientiarum. Health Sciences, Vol 38, Iss 1 (2016) |
| ISSN: | 1807-8648 1679-9291 |
| Popis: | The aim was to assess whether the low level laser therapy (LLLT), 660 nm, can lower the effect of injectable anesthetics in rats. Wistar rats (n = 20) were used in two steps: 1) grip strength test and measuring the anesthesia time for control (G1A) and irradiated (G1AL) groups; 2) after 15 days, rats received new anesthesia injection and were evaluated for nociception (G2A - control; G2AL - laser). Anesthesia was induced by ketamine hydrochloride (75 mg kg-1) and xylazine (10 mg kg-1), by intraperitoneal injection, according to the body weight. LLLT used was 660 nm at four sites along the right hind limb. Anesthesia time was shorter for the G1AL (p = 0.0031). There were significant differences between pre- and post-intervention in the grip strength test (p < 0.001), but no differences were detected between groups (p = 0.459). For nociception, G2AL achieved higher values than G2A (p = 0.019 and p = 0.032), and also for the comparison between pre-injury values with the following values (p < 0.001) although no significant difference was found between 10 and 60 minutes (p > 0.05). It can be concluded that the LLLT caused no significant reduction on the effect of anesthesia. |
| Databáze: | OpenAIRE |
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