A metastatic breast carcinoma presenting as autoimmune hemolytic anemia
Autor: | Giuseppe Papa, Mario Masi, Gabriella Girelli, Paolo Giudiceandrea, Gaspare Adorno, M. C. Arista, Serelina Coluzzi, Maria Paola Perrone |
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Jazyk: | angličtina |
Rok vydání: | 1991 |
Předmět: |
Oncology
Cancer Research medicine.medical_specialty Cyclophosphamide Anemia medicine.medical_treatment Breast Neoplasms Gastroenterology 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Internal medicine Biopsy Antineoplastic Combined Chemotherapy Protocols medicine Humans Aged Chemotherapy medicine.diagnostic_test business.industry Autoantibody General Medicine medicine.disease Doxorubicin 030220 oncology & carcinogenesis Female Anemia Hemolytic Autoimmune Fluorouracil Autoimmune hemolytic anemia Neoplasm Recurrence Local Breast carcinoma business Mastectomy medicine.drug |
Zdroj: | Scopus-Elsevier |
Popis: | The authors describe the case of a 75-year-old female who was hospitalized for anemia of unknown origin. Physical examination revealed a swelling in the right mammary region, where a mastectomy scar was present from surgery for a breast carcinoma. On admission, laboratory tests disclosed anemia (Hb, 8.5 g/dl), with a reticulocyte count of 65,000/mm3 and slightly increased bilirubin. Immunohematologic study revealed the presence of a red cell autoantibody with anti-D specificity in the serum and in the eluate from the patient's erythrocytes. A biopsy of the swelling was performed and histologic examination showed the presence of metastatic cells of breast carcinoma. The patient was given chemotherapy and radiotherapy. At this writing the anemia was absent, the Immunohematologic study was negative, the swelling was greatly reduced, and no other metastatic lesions of breast carcinoma were present. |
Databáze: | OpenAIRE |
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