In-silico analysis of airflow dynamics and particle transport within a human nasal cavity
| Autor: | Franck Pérot, Sauro Succi, Fabio Sterpone, Simone Melchionna, Anxhelo Diko, Manash Pratim Borthakur |
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| Přispěvatelé: | Laboratoire de biochimie théorique [Paris] (LBT (UPR_9080)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut de biologie physico-chimique (IBPC (FR_550)), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Nasal cavity
Materials science General Computer Science [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph] Dynamics (mechanics) Flow (psychology) Airflow Penetration (firestop) Mechanics 01 natural sciences 010305 fluids & plasmas Theoretical Computer Science Volumetric flow rate Physics::Fluid Dynamics Deposition (aerosol physics) medicine.anatomical_structure Modeling and Simulation 0103 physical sciences medicine Particle size 010306 general physics ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Journal of computational science Journal of computational science, Elsevier, 2021, 54, pp.101411. ⟨10.1016/j.jocs.2021.101411⟩ |
| ISSN: | 1877-7503 1877-7511 |
| Popis: | We present a numerical investigation of the airflow dynamics and particle transport through an averaged human nasal cavity. The effect of particle size and breathing rate on the deposition patterns are explored. The simulations reveal that smaller particles penetrate deeper into the airway, whereas larger particles agglomerate near the anterior portion of the nasal cavity. Increasing the flow rate augmented the penetration of the particles. The complex interplay of the finite particle size and the flow inertia decided the spatial deposition of the particles. The findings from this study demonstrate the efficacy of state-of-art simulation frameworks for targeting respiratory disorders. |
| Databáze: | OpenAIRE |
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