Ileus Management International (IMAGINE): protocol for a multicentre, observational study of ileus after colorectal surgery

Autor: Chapman, S. J., Arthur, T., Chan, E., Fomin, I., Ho, D., Morgan, S., Schachtel, M., Nabi, H., Vasko, P., Zabrak, R., Orhalmi, J., Larsen, H., Nors, J., Martensen, A., Paramasivam, R., Ravn, S., Venara, A., Frey, P. -E., Friedrich, M., Raedeker, L. B., Mihaljevic, A. L., Farina, V., Gavagna, L., Lorenzon, L., Pasquali, S., Pata, F., Pellino, G., Podda, M., Imioni, A., Gro, A., Zaffaroni, G., Schaeff, V., Tto, A., Ivins, A., Zolins, A., Jakubauskas, M., Poskus, T., van Dalen, A. S. H. M., ten Doesschate, S. F. H., van Elst, T. R., Kuiper, S. Z., Bemelman, W. A., Chu, M. J. J., Fagan, P., Wells, C. I., Bissett, I. P., Joao, A. A., Soares, A. S., Carneiro, C., Bautista, O., El Kasmi, Y., Perez-Ajates, S., Espin-Basamy, E., Clerc, D., Hubner, M., Aktas, M. K., Baki, B. E., Ozkan, B. B., Sen, A. Y., Yuksek, B., Gecim, E., Bath, M., Bhangu, A., Borakati, A., Fitzgerald, J., Glasbey, J. C. D., Golding, D., Goodson, R., Kamarajah, S., Khatri, C., Khaw, R., Mclean, K., Mills, E., Nepogodiev, D., Thakral, N., Vaughan-Shaw, P. G., Yasin, I., Pinkney, T. D., Blanco-Colino, R., Hodson, J.
Přispěvatelé: AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA - Cancer Treatment and Quality of Life, Surgery, Chapman, S. J., Arthur, T., Chan, E., Fomin, I., Ho, D., Morgan, S., Schachtel, M., Nabi, H., Vasko, P., Žabrák, R., Örhalmi, J., Larsen, H., Nors, J., Martensen, A., Paramasivam, R., Ravn, S., Venara, A., Frey, P. -E., Friedrich, M., Raedeker, L. B., Mihaljevic, A. L., Farina, V., Gavagna, L., Lorenzon, L., Pasquali, S., Pata, F., Pellino, G., Podda, M., Imioni, A., Grò, A., Zaffaroni, G., Schaeff, V., Tto, A., Ivins, A., Zolins, A., Jakubauskas, M., Poskus, T., van Dalen, A. S. H. M., ten Doesschate, S. F. H., van Elst, T. R., Kuiper, S. Z., Bemelman, W. A., Chu, M. J. J., Fagan, P., Wells, C. I., Bissett, I. P., João, A. A., Soares, A. S., Carneiro, C., Bautista, O., El Kasmi, Y., Pérez-Ajates, S., Espín-Basamy, E., Clerc, D., Hübner, M., Aktas, M. K., Baki, B. E., Ozkan, B. B., Sen, A. Y., Yuksek, B., Geçim, E., Bath, M., Bhangu, A., Borakati, A., Fitzgerald, J., Glasbey, J. C. D., Golding, D., Goodson, R., Kamarajah, S., Khatri, C., Khaw, R., Mclean, K., Mills, E., Nepogodiev, D., Thakral, N., Vaughan-Shaw, P. G., Yasin, I., Pinkney, T. D., Blanco-Colino, R., Hodson, J., Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Hémodynamique, Interaction Fibrose et Invasivité tumorales Hépatiques (HIFIH), Université d'Angers (UA), EuroSurg Collaborative, Frey, P.E., Raedeker, L.B., Mihaljevic, A.L., Simioni, A., Sgrò, A., van Dalen, A., Ten Doesschate, S., van Elst, T.R., Kuiper, S.Z., Bemelman, W.A., Chu, M., Wells, C.I., Bissett, I.P., João, A.A., Soares, A.S., Aktas, M.K., Baki, B.E., Ozkan, B.B., Sen, A.Y., Glasbey, J., McLean, K., Vaughan-Shaw, P.G., Pinkney, T.D.
Jazyk: angličtina
Rok vydání: 2018
Předmět:
colorectal surgery
gastrointestinal recovery
postoperative ileus
Male
[SDV]Life Sciences [q-bio]
Anti-Inflammatory Agents
Ileu
030230 surgery
Cohort Studies
Postoperative Complications
0302 clinical medicine
Colon surgery
Medicine
Prospective Studies
Prospective cohort study
Anti-Inflammatory Agents
Non-Steroidal
Gastroenterology
Colorectal surgery
3. Good health
Europe
Elective Surgical Procedures
030220 oncology & carcinogenesis
Female
Non-Steroidal
Cohort study
Human
Adult
medicine.medical_specialty
Ileus
Colon
03 medical and health sciences
Anti-Inflammatory Agents
Non-Steroidal/adverse effects
Anti-Inflammatory Agents
Non-Steroidal/therapeutic use
Australasia
Colon/pathology
Colon/surgery
Colorectal Surgery/adverse effects
Elective Surgical Procedures/adverse effects
Humans
Ileus/therapy
Postoperative Complications/etiology
Postoperative Complications/therapy
Recovery of Function/drug effects
Rectum/pathology
Rectum/surgery
Adverse effect
Elective Surgical Procedure
business.industry
General surgery
Rectum
Recovery of Function
medicine.disease
Prospective Studie
postoperative ileu
Observational study
Postoperative Complication
Cohort Studie
Gastrointestinal function
business
Zdroj: Colorectal disease, 20(1), O17-O25. Wiley-Blackwell
EuroSurg Collaborative 2018, ' Ileus Management International (IMAGINE) : protocol for a multicentre, observational study of ileus after colorectal surgery ', Colorectal Disease, vol. 20, no. 1, pp. O17-O25 . https://doi.org/10.1111/codi.13976
Colorectal Disease
Colorectal Disease, 2018, 20 (1), pp.O17-O25. ⟨10.1111/codi.13976⟩
Colorectal disease, vol. 20, no. 1, pp. O17-O25
ISSN: 1462-8910
1463-1318
DOI: 10.1111/codi.13976
Popis: International audience; AIM: The management of postoperative ileus following colorectal surgery remains controversial. It is the commonest complication after elective colorectal resection and is associated with an increased incidence of postoperative adverse events. The prevention and management of postoperative ileus remains unstandardized. This study aims to describe an international profile of gastrointestinal recovery after colorectal surgery and will assess the role of non-steroidal anti-inflammatory drugs, when used as postoperative analgesia, in expediting the return of gastrointestinal function.METHODS: A multicentre, student- and trainee-led, prospective cohort study will be conducted across both Europe and Australasia. Adult patients undergoing elective colorectal resection during 2-week data collection periods between January and April 2018 will be included. A site-specific questionnaire will capture compliance to Enhanced Recovery after Surgery components at participating centres. The primary outcome is time to gastrointestinal recovery, measured using a composite outcome of bowel function and oral tolerance. The impact of non-steroidal anti-inflammatory drugs on gastrointestinal recovery will be evaluated along with safety data with respect to anastomotic leak, acute kidney injury and complications within 30days of surgery.DISCUSSION: This protocol describes the methodology of an international, observational assessment of gastrointestinal recovery after colorectal surgery. It discusses key challenges and describes how the results will impact on future investigation. The study will be conducted across a large student- and trainee-led collaborative network, with prospective quality assurance and data validation strategies.
Databáze: OpenAIRE
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