A Toxicopathologic Study in Animals After Brief Single Exposures to Hydrogen Fluoride

Autor:	Frank T. Wilinski, Mitchell J. Rosenholtz, Duane F. Ford, Maurice H. Weeks, Theophilus R. Carson, Fred W. Oberst
Rok vydání:	1963
Předmět:	Pathology medicine.medical_specialty Necrosis Conjunctiva Chemistry Public Health Environmental and Occupational Health Histology Inflammation Hyperplasia medicine.disease Hydrofluoric Acid Fluorides medicine.anatomical_structure Toxicity medicine Animal studies medicine.symptom Nose
Zdroj:	American Industrial Hygiene Association Journal. 24:253-261
ISSN:	0002-8894
DOI:	10.1080/00028896309342961
Popis:	The LC50 values for single exposures to HF were found to be 4970, 2690, 2040, and 1310 ppm for rats exposed respectively for periods of 5, 15, 30 and 60 minutes. Rats, dogs and rabbits were exposed also to concentrations of 6% to 50% of the LC50 values for rats. Signs of intoxication and pathology are described. Renal and hepatic lesions were noted. Human sensory levels may be more sensitive than animal studies in estabishing tolerable levels for brief human exposures.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5968ad789ff3f87e613facebd5f93b91 https://doi.org/10.1080/00028896309342961 Zobrazit plný text záznamu