Function of BMPs and BMP Antagonists in Adult Bone

Autor:	Etsuko Abe
Rok vydání:	2006
Předmět:	medicine.medical_specialty Bone Development General Neuroscience Wnt signaling pathway Embryonic Development Osteoblast Biology Bone morphogenetic protein General Biochemistry Genetics and Molecular Biology Bone remodeling Cell biology BMPR2 Endocrinology medicine.anatomical_structure History and Philosophy of Science Internal medicine Catenin Bone Morphogenetic Proteins medicine Animals Humans Bone Remodeling Normal Bone Remodeling Function (biology)
Zdroj:	Annals of the New York Academy of Sciences. 1068:41-53
ISSN:	0077-8923
DOI:	10.1196/annals.1346.007
Popis:	The expression and function of BMPs and BMPs in bone tissues have been studied for a long time because of their remarkable activities. However, their biological functions in normal bone remodeling in adults were not fully understood until recently. Advanced technologies using gene manipulation were used to study their roles in adulthood. In addition, findings of new BMP antagonists and the effect of Wnt-canonical pathways on bone features also provided new insights in bone studies.
Databáze:	OpenAIRE
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