ACE inhibitor-induced small bowel angioedema, mimicking an acute abdomen
| Autor: | Armando Medeiros, Maria Inês Leite, Rafaela Parreira, Luís Amaral, Rui Amaral, Teresa Eloi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Abdominal pain AcademicSubjects/MED00910 Angioedema business.industry Nausea Case Report Gastroenterology 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Acute abdomen Internal medicine Ascites ACE inhibitor medicine Perindopril Vomiting Surgery jscrep/0160 medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Surgical Case Reports |
| ISSN: | 2042-8812 |
| DOI: | 10.1093/jscr/rjaa348 |
| Popis: | Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema, being the face, tongue, lips and upper airway the most affected ones. We describe a case of a 32-year-old white female with angioedema of small intestine after 1 month of perindopril therapy. The patient presented severe abdominal pain, nausea and vomiting. Laboratory analyses revealed mild leukocytosis and abdominal computed tomography (CT) showed unspecific findings, including segmental jejunal wall thickening without obstruction and ascites. Regarding the clinical findings, similar to an acute abdomen with no clear cause, the patient underwent an emergency laparoscopy that excluded other pathological features. The symptoms recurred 1 month after and the CT scan revealed the same pattern. Perindopril was stopped and the patient improved, concluding that ACE inhibitor-induced visceral angioedema was responsible for this clinical presentation. |
| Databáze: | OpenAIRE |
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