| Popis: |
Objective: The research objective is the assessment of multiple sclerosis, presented clinically. Methodology: Our research uses hospital-based observation at Services Hospital, Lahore (Neurology Dept. from March, 2016 to February, 2017) studying patients with multiple sclerosis, diagnosed on the criteria of Poser. The basis of our observation includes gender, age, family history, clinical course, symptoms and signs, visual evoked potentials, MRI, oligo-clonal band and cerebrospinal fluid. Results: The subject size was twenty including thirteen females and 1:2 Male ratio Female. At clinical presentation, mean age was recorded as 25.80 years, visual defect seventy percent, paroxysmal spasm twenty-five, sensory impairment thirty-five, sphincter disturbances sixty, cerebellar signs thirty, and pyramidal weakness seventy-five percent each. The presentation of MS included secondary Progressive MS, Relapsing and Remitting MS, Primary Progressive MS and Progressive Relapsing MS with a percentage of 20, 55, 15, and 10 respectively. Results of 5%, 55%, 75%, 85%, and 100% reported positive in oligo clonal bands, MRI, OS type, visual evoked potential abnormality, and cervico-dorsal respectively. Conclusions: MS is very common in Pakistan with the ratio of affection between female and male as 2:1 respectively (mean age: 25.80). Clinical results with oligo clonal band at low yield and high optico-spinal occurrence are in agreement with variety of diseases in Asia. Key Words: Cervico-Dorsal (CD), Optico-Spinal (OS), Multiple Sclerosis (MS), Oligo clonal Bands (OB), Magnetic Resonance Imaging (MRI), Cerebral Spinal Fluid (CSF) and Central Nervous System (CNS). |
