Is Carotid Stenosis in Women a Gender-Related Condition?
| Autor: | Demetra Kiltzanidi, Francesco Tartaglia, Giovanni Carbotta, Giovanni Tortorelli, Luciana Tromba, S Carbotta, Stefania Cavaiola, Fabio Pelle, Alessandro Giuliani, Sara Blasi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Carotid Artery Diseases
Male Hyperpnea 030204 cardiovascular system & hematology 0302 clinical medicine Risk Factors 80 and over Prevalence Medicine Carotid Stenosis Plaque Atherosclerotic Aged 80 and over Hypertriglyceridemia Ultrasound Apnea General Medicine Middle Aged Plaque Atherosclerotic Carotid Arteries Italy Hypertension cardiovascular system epidemiology Female Radiology medicine.symptom Adult medicine.medical_specialty diagnostic imaging Hypercholesterolemia 03 medical and health sciences Age Distribution Sex Factors Heart rate Diabetes Mellitus Humans Aged Carotid Arteries diagnostic imaging Carotid Artery Diseases diagnostic imaging Carotid Stenosis diagnostic imaging Carotid Stenosis epidemiology Carotid Stenosis pathology Case-Control Studies Diabetes Mellitus epidemiology Hypercholesterolemia epidemiology Hypertension physiopathology Hypertriglyceridemia epidemiology Plaque Atherosclerotic epidemiology Tunica Intima pathology pathology business.industry Case-control study Echogenicity medicine.disease Stenosis physiopathology Tunica Intima business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Women's Health. 25:348-354 |
| ISSN: | 1931-843X 1540-9996 |
| Popis: | We set out to study, through ultrasound examinations, the carotid bifurcation in men and women with/without carotid stenosis to look for anatomical and electrophysiologic differences. We evaluated other variables to look for differences that might explain the dissimilar behavior of this disease in the two sexes and the presence and impact of risk factors.We examined 974 subjects aged 25 to 88 years (478 men and 496 women) in whom we considered heart rate, smoking status, and the presence of hypertension, diabetes, hypercholesterolemia, and hypertriglyceridemia. Ultrasound examination of the neck vessels included measurement of intimal medial thickness (IMT), vessel diameter, and outflow area/inflow area ratio. We established plaque location, echogenicity and echostructure, and the percentage of stenosis owing to plaque and measured systolic velocity, flow direction, and the depth of detection of these parameters. We used the apnea and hyperpnea test to assess cerebrovascular reactivity.Hypertension and hypercholesterolemia were the most frequent risk factors. Women had a higher heart rate, whereas men had significantly greater IMT. The presence of atheromatous plaque was significantly correlated with age in both sexes, with men having a higher prevalence of carotid plaques. The sexes differed significantly with regard to plaque location, echogenicity, echostructure, and intracranial circulation. Women had a slightly higher blood flow velocity in the intracranial arteries. Risk factors affected plaque formation and extent more in men than in women.These findings suggest that carotid stenosis is a gender-related trait. |
| Databáze: | OpenAIRE |
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