Additional file 1 of Glioma cells require one-carbon metabolism to survive glutamine starvation

Autor: Tanaka, Kazuhiro, Sasayama, Takashi, Nagashima, Hiroaki, Irino, Yasuhiro, Takahashi, Masatomo, Izumi, Yoshihiro, Uno, Takiko, Satoh, Naoko, Kitta, Akane, Kyotani, Katsusuke, Fujita, Yuichi, Hashiguchi, Mitsuru, Nakai, Tomoaki, Kohta, Masaaki, Uozumi, Yoichi, Shinohara, Masakazu, Kohkichi Hosoda, Bamba, Takeshi, Kohmura, Eiji
Rok vydání: 2021
Předmět:
DOI: 10.6084/m9.figshare.13612770.v1
Popis: Additional File 1. Supplementary figures. Fig. S1: Metabolomic analysis in the ‘central’ and ‘edge’ of tumor of GBM patients. Fig. S2: Serine and glycine levels in glioma cells treated with glutamine starvation and hypoxia. Fig. S3: MTHFD2 expressions after glutamine starvation in GBM patient-derived sphere cells. Fig. S4: Reactive oxygen species (ROS) status and nucleotide biosynthesis in glutamine-deprived GBM cells. Fig. S5: The role of autophagy in one-carbon metabolism of GBM cells to survive glutamine deprivation.
Databáze: OpenAIRE