Comparable characteristics of tuberculous and non-tuberculous mycobacterial cavitary lung diseases
| Autor: | Hyun-Ju Choi, D. J. Im, Young Uh, Sowon Hahn, HyoYoul Kim, Young Keun Kim, Y. L. Lim |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine China medicine.medical_specialty Time Factors Tuberculosis Adolescent Antitubercular Agents Mycobacterium Infections Nontuberculous Disease Diagnosis Differential Young Adult Predictive Value of Tests Risk Factors Internal medicine Odds Ratio medicine Humans Young adult Lung Respiratory Tract Infections Tuberculosis Pulmonary Aged Aged 80 and over Chi-Square Distribution medicine.diagnostic_test business.industry Age Factors Sputum Nontuberculous Mycobacteria Mycobacterium tuberculosis Odds ratio Middle Aged bacterial infections and mycoses medicine.disease Radiography Logistic Models Infectious Diseases medicine.anatomical_structure Predictive value of tests Multivariate Analysis Female Chest radiograph business Chi-squared distribution |
| Zdroj: | The International Journal of Tuberculosis and Lung Disease. 18:725-729 |
| ISSN: | 1027-3719 |
| DOI: | 10.5588/ijtld.13.0871 |
| Popis: | Objective To identify characteristics that differentiate lung disease due to non-tuberculous mycobacteria (NTM) from that due to pulmonary tuberculosis (PTB) in acid-fast bacilli (AFB) smear-positive patients with lung cavities. Methods From 2006 to 2012, 142 AFB smear- and culture-positive patients with lung cavities were identified at the Wonju Severance Christian Hospital, Wonju, Korea. Clinical and radiographic characteristics were compared between patients with NTM disease and PTB. Results Of 142 patients, 112 were diagnosed with PTB and 30 with NTM disease. Patients with NTM disease were older (62 vs. 49 years, P = 0.001), more likely to have had previous anti-tuberculosis treatment (18, 60.0% vs. 34, 30.6%; P = 0.001), more likely to have haemoptysis (9, 30.0% vs. 13, 11.9%; P = 0.022) and less likely to have consolidation on chest radiograph (20, 66.7% vs. 98, 87.5%; P = 0.007) than PTB patients. Multivariate analysis showed that age ≥65 years (OR 3.37, 95%CI 1.24-9.13, P = 0.010) and previous anti-tuberculosis treatment (OR 3.75, 95%CI 1.46-9.65, P = 0.006) were significantly associated with NTM disease. Conclusions Cavitary patients with positive AFB smears and NTM or PTB had considerable overlapping clinical characteristics, although patients aged ≥65 years or with a previous history of anti-tuberculosis treatment were more likely to have NTM. |
| Databáze: | OpenAIRE |
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