2,4,6-Tribromophenol is toxic to Oreochromis niloticus (Linnaeus, 1758) after trophic and subchronic exposure
| Autor: | Elton Celton de Oliveira, Maristela Azevedo-Linhares, Nilce Mary Turcatti Folle, Francisco Filipak Neto, Luíse Esquivel, Sonia Regina Grötzner, Ciro Alberto de Oliveira Ribeiro, Juan Ramon Esquivel Garcia |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Environmental Engineering Antioxidant Health Toxicology and Mutagenesis medicine.medical_treatment 0208 environmental biotechnology 02 engineering and technology 010501 environmental sciences 01 natural sciences Lipid peroxidation chemistry.chemical_compound Vitellogenin Phenols Internal medicine medicine Environmental Chemistry Animals 0105 earth and related environmental sciences Cholinesterase biology Superoxide Dismutase Public Health Environmental and Occupational Health General Medicine General Chemistry Glutathione Cichlids biology.organism_classification Catalase Pollution 020801 environmental engineering Oreochromis Oxidative Stress Endocrinology chemistry Liver Toxicity biology.protein Female Lipid Peroxidation Water Pollutants Chemical |
| Zdroj: | Chemosphere. 268 |
| ISSN: | 1879-1298 |
| Popis: | The presence of 2,4,6-Tribromophenol (TBP) in the environment increased the risk of exposure to aquatic organisms affecting the animal development or metabolism. The current study investigated the low, subchronic and trophic effect of TBP in both, male and female adult of Oreochromis niloticus. The fish were exposed to 0.5 or 50 ng g−1 of TBP every ten days for 70 days. Then, hepatosomatic (HSI) and gonadosomatic (GSI) indexes, erythrocyte parameters (hemoglobin content, nuclear morphology and morphometrical abnormalities), biochemical endpoints (glutathione S-Transferase and catalase activities, non-protein thiols, lipid peroxidation and protein carbonylation levels in the liver; and acetylcholinesterase activity in the brain and muscle), histopathological analysis (liver) and vitellogenin levels (plasma) were considered. TBP affected the HSI in male and female fish, but not the GSI. Principal Component Analysis revealed that erythrocytes from males are more sensitive to TBP exposure. Likewise, TBP induced the expression of vitellogenin, CAT activity and liver lesion in male fish comparatively with control group, but GST and NPT were influenced only by sex. Finally, the results showed that the antioxidant mechanism and cholinesterase activity effects were more pronounced in male than in female. The current data shows evidences of estrogenic endocrine disruption and toxicity in O. niloticus exposed to TBP, revealing the risk of exposure to biota. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect