The incidence of lung tumours in C57BL mice exposed to cigarette smoke:Air mixtures for prolonged periods
| Autor: | Susan Ludgate, F. C. Chesterman, G. Negroni, R. J. C. Harris, B. J. Maidment, C. R. Pick |
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| Rok vydání: | 1974 |
| Předmět: |
Adenoma
Male Cancer Research Lung Neoplasms Physiology Toxicology Mice Untreated control Smoke Animals Cigarette smoke Medicine Lung business.industry Air Incidence (epidemiology) Carcinoma Smoking Age Factors Mice Inbred C57BL medicine.anatomical_structure Oncology Female Lung tumours business Filtration |
| Zdroj: | International Journal of Cancer. 14:130-136 |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/ijc.2910140116 |
| Popis: | C57BI mice, allowed to breathe a cigarette smoke:air mixture for short periods and at frequent intervals throughout their lives, develop a higher incidence of lung cancers, adenomas and carcinomas, than untreated control animals. Smoke from cigarettes made from a flue-cured tobacco (T2) was more toxic and elicited cancers more quickly than that from cigarettes made from air-dried tobacco (T3) from the same crop. Filtered smoke :air from T2 and unfiltered smoke gave similar yields of lung tumours. |
| Databáze: | OpenAIRE |
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