Effects of Vitamin D Supplementation on Serum 25-Hydroxyvitamin D Concentrations and Physical Performance in Athletes: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Autor: | Devin Peterson, Gayathri K Sivakumar, Mohit Bhandari, Forough Farrokhyar, Alex Koziarz, Olufemi R. Ayeni, Katey Savage, Sahab Jamshidi |
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Rok vydání: | 2017 |
Předmět: |
Adult
Male medicine.medical_specialty Sports medicine Adolescent 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation Athletic Performance Placebo Gastroenterology law.invention 03 medical and health sciences Young Adult 0302 clinical medicine Randomized controlled trial law Tandem Mass Spectrometry Internal medicine Vitamin D and neurology medicine Humans Orthopedics and Sports Medicine Young adult Vitamin D Randomized Controlled Trials as Topic biology Athletes business.industry 030229 sport sciences biology.organism_classification Confidence interval Endocrinology Meta-analysis Dietary Supplements Female business |
Zdroj: | Sports medicine (Auckland, N.Z.). 47(11) |
ISSN: | 1179-2035 |
Popis: | There is currently no systematic review examining the effects of vitamin D supplementation among athletes. A rigorous systematic review and meta-analysis is important to provide a balanced view of current knowledge on the effect of vitamin D on serum 25-hydroxyvitamin D [25(OH)D] concentrations and physical performance. This systematic review of randomized controlled trials (RCTs) evaluated the effects of oral vitamin D supplementation on serum 25(OH)D concentrations and physical performance in athletes. Multiple electronic databases were searched, and study eligibility, methodological quality assessment, and data extraction were completed independently and in duplicate. Studies were stratified by baseline vitamin D sufficiency, season, and latitude. A cut-off of 30 ng/ml (75 nmol/l) of 25(OH)D was used for sufficiency. Absolute mean differences (AMDs) between vitamin D and placebo using random effects analysis, and heterogeneity using Q statistic and I 2 index, were calculated. AMD with 95% confidence interval (CI), p value, and I 2 are reported. In total, 13 RCTs (2005–2016) with 532 athletes (vitamin D 311, placebo 221) were eligible. A total of 433 athletes (vitamin D 244, placebo 189) had complete outcome data. Among athletes with baseline values suggesting insufficiency, vitamin D supplementation led to significant increases from 3000 IU (AMD 15.2 ng/ml; 95% CI 10.7–19.7, p 45° latitudes. Both doses led to sufficiency concentrations during winter months. Among athletes with baseline vitamin D suggesting sufficiency, serum 25(OH)D sufficiency was maintained from different doses at both latitudes. Of 13 included trials, only seven measured different physical performances and none demonstrated a significant effect of vitamin D supplementation during 12 weeks of follow-up. Despite achieving sufficiency in vitamin D concentrations from ≥3000 IU supplementation, physical performance did not significantly improve. Between-study heterogeneity was large, and well-designed RCTs examining the effect of vitamin D supplementation on serum 25(OH)D concentrations, physical performance, and injuries in different sports, latitudes, ethnicities, and vitamin D status are needed. |
Databáze: | OpenAIRE |
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