Femur absorptiometry changes determined by X-ray image segmentation in mice under experimental diabetes and ovariectomy
| Autor: | Rigoberto Oros-Pantoja, Luis Alberto Medina-Velázquez, Eugenio Torres-García, Mario Flores-Reyes, Luis Enrique Díaz-Sánchez, Alfredo V. Mercado-Quintero |
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| Rok vydání: | 2021 |
| Předmět: |
endocrine system diseases
Ovariectomy Osteoporosis 010403 inorganic & nuclear chemistry 01 natural sciences Diabetes Mellitus Experimental 030218 nuclear medicine & medical imaging Mice 03 medical and health sciences Absorptiometry Photon 0302 clinical medicine Bone Density Diabetes mellitus medicine Animals Femur Radiation business.industry Type 2 Diabetes Mellitus medicine.disease 0104 chemical sciences Disease Models Animal X ray image Female Nuclear medicine business Experimental diabetes |
| Zdroj: | Applied Radiation and Isotopes. 170:109608 |
| ISSN: | 0969-8043 |
| DOI: | 10.1016/j.apradiso.2021.109608 |
| Popis: | Aim The aim of the present work was to determine if both ovariectomy (OVX) and type 2 diabetes mellitus (T2DM) can change X-ray absorptiometry until reach the osteoporosis condition. Results The segmentation allowed us to quantitatively determine the X-ray absorption in the femurs of mice subjected to OVX, T2DM and both pathologies together. Conclusions The test subjects suffering from the mentioned pathologies separately or together, did not reach the osteoporosis condition when they were 30 weeks old. |
| Databáze: | OpenAIRE |
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