Perventricular device closure of isolated muscular ventricular septal defect in infants: A single centre experience☆
Autor: | Nehal H Patel, Tarun Madan, Chirag Shah, Shaunak B Shah, Anand Shukla, Bhavesh Thakkar, Vaishali J Prajapati, Vishal Poptani |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
Heart Septal Defects
Ventricular Male medicine.medical_specialty RD1-811 Septal Occluder Device Treatment outcome Closure (topology) Muscular VSD Internal medicine MUSCULAR VENTRICULAR SEPTAL DEFECT medicine Diseases of the circulatory (Cardiovascular) system Humans cardiovascular diseases Prospective cohort study Congenital heart disease business.industry Surgery Single centre Perventricular RC666-701 Cardiology Hybrid interventions Original Article Female business Cardiology and Cardiovascular Medicine Infants |
Zdroj: | Indian Heart Journal, Vol 64, Iss 6, Pp 559-567 (2012) |
Popis: | Objectives: To evaluate prospective single centre experience of mid-term safety and efficacy of perventricular device closure of isolated large muscular ventricular septal defect (mVSD) in high-risk infants. Background: Surgical closures of large mVSD in infants represent a challenge with significant morbidity. Methods: Between August 2008–2010, perventricular closure was attempted in 24 infants of 6.01 ± 2.37 months age and 4.27 ± 0.56 kg weight under TEE guidance. Results: The device was successfully deployed in 21/24 infants. Size of mVSD was 8.42 ± 1.46 mm (6.1–12 mm). Mean procedure time was 28.8 ± 11.7 min. The closure rate was 84% immediately and 100% at 6 months. Four patients suffered major complications: 2-died, 1-esophageal perforation, 1-persistent CHB. At 26.23 ± 6.63 months follow-up two patients were symptomatic: 1-required device retrieval, 1-died of severe gastroenteritis. Conclusion: Perventricular device closure of isolated mVSD appears feasible option at mid-term follow-up and may either substitute or complement the conventional surgical technique in selected cases depending on institutional paediatric cardiac surgery performance. |
Databáze: | OpenAIRE |
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