The effect of the phytoalexins, lubimin, (−)-maackiain, pinosylvin, and the related compounds dehydroloroglossol and hordatine M on human lymphoblastoid cell lines
Autor: | A. Stoessl, L. Skinnider |
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Rok vydání: | 1986 |
Předmět: |
Agmatine
Pterocarpans Stereochemistry Pinosylvin Biology Dehydroloroglossol Cell Line Cellular and Molecular Neuroscience chemistry.chemical_compound Phytoalexins Stilbenes Humans Benzopyrans Lymphocytes Molecular Biology Pharmacology chemistry.chemical_classification Plant Extracts Terpenes Cell growth Phytoalexin Cell Biology Phenanthrenes Hordatine M chemistry Lymphoblastoid cell Biochemistry Cinnamates Cell culture Protein Biosynthesis Molecular Medicine Thymidine Sesquiterpenes Cell Division |
Zdroj: | Experientia. 42:568-570 |
ISSN: | 1420-9071 0014-4754 |
DOI: | 10.1007/bf01946707 |
Popis: | We have tested the effect of the phytoalexins lubimin, (-)-maackiain and pinosylvin and the related compounds dehydroloroglossol and hordatine M on the growth of the human lymphoblastoid cell lines Molt and Raji. (-)-maackiain, pinosylvin and dehydroloroglossol showed significant growth inhibitory action on the cells. Suppression of [3H] thymidine and [3H] leucine uptake was tested and noted in pinosylvin and dehydroloroglossol. The phytoalexins and related compounds are widespread in plants and provide a potential source of antineoplastic substances. |
Databáze: | OpenAIRE |
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