Normal CD4 Count Range among Healthy Nigerian Population in Ilorin
| Autor: | AS Babatunde, HO Olawumi, SK Ernest, IA Durotoye, M. A. N. Adeboye, R. Saadu, Olufemi Olumuyiwa Desalu, Sunday A Aderibigbe, A E Fawibe, Alakija K Salami, A. P. Aboyeji, JK Afolabi, Abayomi Fadeyi |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Adolescent Immunology Blood count Nigeria Dermatology lcsh:RC870-923 Young Adult 03 medical and health sciences Sex Factors Animal science Reference Values Humans Medicine Child Aged Immune status business.industry Nigerians Age Factors Infant Nigerian population Middle Aged lcsh:Diseases of the genitourinary system. Urology CD4 Lymphocyte Count Cross-Sectional Studies 030104 developmental biology Infectious Diseases Child Preschool Reference values Female business Demography |
| Zdroj: | Journal of the International Association of Providers of AIDS Care, Vol 16 (2017) |
| ISSN: | 2325-9582 2325-9574 |
| Popis: | Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm3 (19%-48%) and for children was 582 to 3652 cells/mm3 (17%-50%). CD4 count and percentage of CD4 were significantly ( P = .001) higher in females than in males, and the CD4 count declined significantly with increasing age ( r = −.174, P ≤ .0001). The percentage of CD4 count shows less variation with age ( r = −.051, P = .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 ± 260) than that of the national reference values of 847.0 ± 307.0 cells/mm3 ( P = .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values. |
| Databáze: | OpenAIRE |
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