Micronutrient supplementation adherence and influence on the prevalences of anemia and iron, zinc and vitamin A deficiencies in preemies with a corrected age of six months

Autor: Maria Elisabeth Lopes Moreira, Jusceli Souza Nogueira Sabino, Silvia Eloiza Priore, Luciana Moreira Lima, Bruno David Henriques, Brunnella Alcantara Chagas de Freitas, Carla Fernanda Lisboa Valente Carlos, Sylvia do Carmo Castro Franceschini
Rok vydání: 2016
Předmět:
Male
0301 basic medicine
Pediatrics
Time Factors
anemia
iron deficiency

chemistry.chemical_compound
0302 clinical medicine
Reference Values
Risk Factors
Prevalence
zinc deficiency
Medicine
Prospective Studies
Micronutrients
Vitamin A
Prospective cohort study
lcsh:R5-920
Anemia
Iron-Deficiency

Anemia
Neonatal

Vitamin A Deficiency
Age Factors
Anemia
Iron Deficiencies
General Medicine
Iron deficiency
Clinical Science
Zinc Deficiency
Micronutrient
vitamin a
Zinc
Treatment Outcome
Regression Analysis
Female
lcsh:Medicine (General)
Multivitamin
Anemia
Iron Deficiency

Brazil
Infant
Premature

Vitamin
medicine.medical_specialty
Iron
Statistics
Nonparametric

Medication Adherence
premature
03 medical and health sciences
030225 pediatrics
Humans
Premature
030109 nutrition & dietetics
business.industry
Infant
medicine.disease
infant
Vitamin A deficiency
Socioeconomic Factors
chemistry
micronutrients
Dietary Supplements
medication adherence
Zinc deficiency
business
Zdroj: Clinics, Vol 71, Iss 8, Pp 440-448
Clinics; v. 71 n. 8 (2016); 440-448
Clinics; Vol. 71 Núm. 8 (2016); 440-448
Clinics; Vol. 71 No. 8 (2016); 440-448
Clinics
Universidade de São Paulo (USP)
instacron:USP
Clinics, Volume: 71, Issue: 8, Pages: 440-448, Published: AUG 2016
LOCUS Repositório Institucional da UFV
Universidade Federal de Viçosa (UFV)
instacron:UFV
ISSN: 1807-5932
1980-5322
Popis: OBJECTIVE: To analyze adherence to the recommended iron, zinc and multivitamin supplementation guidelines for preemies, the factors associated with this adherence, and the influence of adherence on the occurrence of anemia and iron, zinc and vitamin A deficiencies. METHODS: This prospective cohort study followed 58 preemies born in 2014 until they reached six months corrected age. The preemies were followed at a referral secondary health service and represented 63.7% of the preterm infants born that year. Outcomes of interest included high or low adherence to iron, zinc and multivitamin supplementation guidelines; prevalence of anemia; and prevalences of iron, zinc, and vitamin A deficiencies. The prevalence ratios were calculated by Poisson regression. RESULTS: Thirty-eight (65.5%) preemies presented high adherence to micronutrient supplementation guidelines. At six months of corrected age, no preemie had vitamin A deficiency. The prevalences of anemia, iron deficiency and zinc deficiency were higher in the low-adherence group but also concerning in the high-adherence group. Preemies with low adherence to micronutrient supplementation guidelines were 2.5 times more likely to develop anemia and 3.1 times more likely to develop zinc deficiency. Low maternal education level increased the likelihood of nonadherence to all three supplements by 2.2 times. CONCLUSIONS: Low maternal education level was independently associated with low adherence to iron, zinc and vitamin A supplementation guidelines in preemies, which impacted the prevalences of anemia and iron and zinc deficiencies at six months of corrected age.
Databáze: OpenAIRE