Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review
Autor: | Yue-Yuan Zhao, Wang Zheng, Zhi Tian, Xu-Yang Cao, Li Xicheng, Ya-Zhou Zhang, Jia Chen |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
lcsh:Diseases of the musculoskeletal system Diagnostic accuracy Sensitivity and Specificity Likelihood ratios in diagnostic testing 030218 nuclear medicine & medical imaging 03 medical and health sciences Femoral head Magnetic resonance imaging 0302 clinical medicine lcsh:Orthopedic surgery Femur Head Necrosis medicine Humans Orthopedics and Sports Medicine Prospective cohort study 030222 orthopedics medicine.diagnostic_test Receiver operating characteristic business.industry Reproducibility of Results lcsh:RD701-811 Meta-analysis Early osteonecrosis of the femoral head medicine.anatomical_structure Orthopedic surgery Diagnostic odds ratio Surgery Systematic Review Radiology lcsh:RC925-935 business |
Zdroj: | Journal of Orthopaedic Surgery and Research Journal of Orthopaedic Surgery and Research, Vol 13, Iss 1, Pp 1-8 (2018) |
ISSN: | 1749-799X |
DOI: | 10.1186/s13018-018-0836-8 |
Popis: | Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). Summary receiver operating characteristic (SROC) analyses were performed for meniscal tears. Results Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. The global sensitivity and specificity of MRI in early osteonecrosis of the femoral head were 93.0% (95% CI 92.0–94.0%) and 91.0% (95% CI 89.0%–93.0%), respectively. The global positive likelihood ratio and global negative likelihood ratio of MRI in early osteonecrosis of the femoral head were 2.74 (95% CI 1.98–3.79) and 0.18 (95% CI 0.14–0.23), respectively. The global DOR was 27.27 (95% CI 17.02–43.67), and the area under the SROC was 93.38% (95% CI 90.87%–95.89%). Conclusions This review provides a systematic review and meta-analysis to evaluate the diagnostic accuracy of MRI in early osteonecrosis of the femoral head. Moderate to strong evidence indicated that MRI appears to be significantly associated with higher diagnostic accuracy for early osteonecrosis of the femoral head. |
Databáze: | OpenAIRE |
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