Atorvastatin decreases cellular proliferation and bone matrix expression in the hypercholesterolemic mitral valve

Autor:	Babu Makkena, Thomas C. Spelsberg, Nalini M. Rajamannan, Malayannan Subramaniam, Frank C. Caira, Senthil Thennapan, Robert H. Bonow, Hani I. Salti, Robert O. Bonow
Rok vydání:	2005
Předmět:	Male medicine.medical_specialty Atorvastatin Hypercholesterolemia Heart Valve Diseases chemistry.chemical_element Bone Matrix Autopsy Bone matrix 030204 cardiovascular system & hematology Calcium Article 03 medical and health sciences 0302 clinical medicine Calcinosis Internal medicine Mitral valve Medicine Animals Pyrroles cardiovascular diseases 030212 general & internal medicine health care economics and organizations business.industry Anticholesteremic Agents medicine.disease Pathophysiology medicine.anatomical_structure chemistry Heptanoic Acids cardiovascular system Cardiology Mitral Valve Rabbits business Cardiology and Cardiovascular Medicine Cell Division Calcification medicine.drug
Zdroj:	Journal of the American College of Cardiology. 45(4):631-633
ISSN:	0735-1097
DOI:	10.1016/j.jacc.2004.11.023
Popis:	To the Editor: Idiopathic calcification of the mitral annulus is one of the most common cardiac abnormalities demonstrated at autopsy ([1][1]). Currently, the pathophysiology of mitral annular calcification (MAC) is viewed as a passive degenerative process due to a buildup of calcium along the
Databáze:	OpenAIRE
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