A new sesquiterpenoid from the aconitum-derived fungus Aspergillus fumigatus M1

Autor: Hao Ding, Jia-Peng Wang, Si-Ping Deng, Jun-Li Gan, Bing-Xian Li, Ling-Ling Yao, Sheng-Qi Zhang, Le Cai, Zhong-Tao Ding
Rok vydání: 2022
Předmět:
Zdroj: Natural Product Research. :1-9
ISSN: 1478-6427
1478-6419
DOI: 10.1080/14786419.2022.2080207
Popis: A new bergamotane sesquiterpenoid, fumigatanol (1), along with nine known compounds (2-10) were isolated from the Aconitum-derived fungus Aspergillus fumigatus M1. Their structures were established on the basis of extensive spectroscopic analyses, ECD experiment and NMR computational method. Antibacterial and cytotoxic activities of compound 1 were evaluated and no obvious antibacterial and cytotoxic activities were observed at concentrations of 256 μg/mL and 40.00 μM, respectively.
Databáze: OpenAIRE