Exhaled Breath Condensate Acidification Occurs During Surgery for Abdominal Cancer
| Autor: | Archontia Mahairidou, Eirini Maratou, Thomas Raptakis, Effrosyni D. Manali, Sophia Rodopoulou, Spyros Papiris, Anna Karakatsani, Ioannis Tomos |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Time Factors Ph changes Bronchospasm Gynecologic Surgical Procedures Predictive Value of Tests Risk Factors Surgical oncology Monitoring Intraoperative medicine Humans Exhaled breath condensate In patient Lung cancer Digestive System Surgical Procedures Aged Proportional Hazards Models Aged 80 and over Bronchial Spasm business.industry Cancer General Medicine Hydrogen-Ion Concentration Length of Stay Middle Aged medicine.disease Confidence interval respiratory tract diseases Surgery Treatment Outcome Breath Tests Oncology Exhalation Abdominal Neoplasms Linear Models Urologic Surgical Procedures Female medicine.symptom business |
| Zdroj: | Anticancer Research. 37 |
| ISSN: | 0250-7005 |
| Popis: | BACKGROUND/AIM Acidification of exhaled breath condensate (EBC), reflecting airway inflammation and oxidative stress, has been reported in lung cancer patients undergoing lobectomy. We undertook this study to examine EBC pH changes during surgery for abdominal cancer. PATIENTS AND METHODS EBC pH was measured from 20 patients undergoing abdominal cancer resection before and during surgery. Repeated-measures of ANOVA and random-effects linear models were applied to compare mean EBC pH values in samples collected at different times. Cox and linear regression models were used to determine the association of EBC pH with occurrence of acute bronchospasm intra-operatively and the duration of hospitalization. RESULTS Significant acidification of EBC was observed during surgery (p=0.007) associated with 0.77% (95% confidence interval=-0.14-1.68, p-value=0.097) increase in the risk for developing acute bronchospasm, after adjustment for potential confounders. CONCLUSION EBC acidification occurs in patients undergoing abdominal cancer resection and is associated with the occurrence of acute bronchospasm intraoperatively. |
| Databáze: | OpenAIRE |
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