Li+-Controlled Diastereoselectivity of the Addition of Allenyl Cuprate Reagents to Aldehydes
| Autor: | Emmanuel Vrancken, Hélène Gérard, Pierre Mangeney |
|---|---|
| Přispěvatelé: | Chimie Organique (CO), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de chimie théorique (LCT), Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Personal account
010405 organic chemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry Allene Organic Chemistry 010402 general chemistry 01 natural sciences Catalysis Transition state 0104 chemical sciences chemistry.chemical_compound chemistry Computational chemistry Reagent homopropargylic alcohols - allene - cuprate - lithium - diastereoselectivity - DFT calculations Organic chemistry Cuprate |
| Zdroj: | Synthesis: Journal of Synthetic Organic Chemistry Synthesis: Journal of Synthetic Organic Chemistry, 2016, 49 (3), pp.526-531. ⟨10.1055/s-0036-1588613⟩ SYNTHESIS SYNTHESIS, Georg Thieme Verlag, 2016, 49 (3), pp.526-531. ⟨10.1055/s-0036-1588613⟩ |
| ISSN: | 0039-7881 1437-210X |
| Popis: | International audience; This personal account summarizes our recent work regarding the addition of allenyl cuprates to aldehydes. An intertwined experimental and theoretical study enables highlighting of the crucial role of Li+ as a structuring agent in the different intermediates and transition states involved, and thus on the diastereochemical outcome of the reaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|