Blue Light Imaging and Linked Color Imaging for the Characterization of Mucosal Changes in Chronic Gastritis: A Clinicians View and Brief Technical Report
Autor: | Alexander Link, Jochen Weigt, Peter Malfertheiner, Ali Canbay, Johannes Haybaeck, Elizabeth L. Bird-Lieberman |
---|---|
Rok vydání: | 2019 |
Předmět: |
Adult
Gastritis Atrophic Male medicine.medical_specialty Light Atrophic gastritis Chronic gastritis Pilot Projects Gastroenterology 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Atrophy Internal medicine Humans Medicine Antrum Aged Aged 80 and over medicine.diagnostic_test business.industry Stomach Intestinal metaplasia Endoscopy Histology General Medicine Middle Aged medicine.disease medicine.anatomical_structure Gastric Mucosa 030220 oncology & carcinogenesis Chronic Disease Female 030211 gastroenterology & hepatology business |
Zdroj: | Digestive Diseases. 38:9-14 |
ISSN: | 1421-9875 0257-2753 |
Popis: | Background: Blue light imaging (BLI) and linked color imaging (LCI) are new imaging modalities for the endoscopic evaluation of mucosal changes within the digestive tract. There is little experience with these modalities in the characterization of chronic gastritis (CG) intestinal metaplasia (IM) and atrophy in the stomach. Aims and Methods: In a single-center observational pilot study, we correlated endoscopic findings with histology in selected patients. Results: Findings from 29 patients were included in the analysis. Six patients had macroscopically normal gastric mucosa at endoscopy, and this was confirmed histologically in 5 of them. At endoscopy, 15 patients had the presence of IM in the antrum predicted, and this was confirmed histologically in 11 (73%). In the corpus, we predicted the presence of IM in 14 patients, and this was confirmed in 11 (78%) at histology. Eleven patients had the endoscopic suspicion of atrophy in antrum, which was confirmed in 9 patients (82%). In total, 14 patients had endoscopic suspicion of atrophy in corpus mucosa at endoscopy, but only 10 were confirmed in histology (71%). The concordance of endoscopic classification and histology was 93% for antrum and 88% for corpus. The positive predictive value and negative predictive value for IM were 0.74 and 0.83 and for atrophy 0.63 and 0.97, respectively. Conclusions: LCI and BLI are helpful in characterization of mucosal changes in CG. The ability to rule out premalignant conditions by endoscopy only reflects the clinical use and harbors significant clinical implications. |
Databáze: | OpenAIRE |
Externí odkaz: |