Serum erythropoietin levels in thalassemia intermedia
| Autor: | Silvana Bonfigli, Fausto Dore, E. Gaviano, Maurizio Roberto Longinotti, Paolo Cianciulli, Giuseppe Papa, Simonetta Pardini |
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| Rok vydání: | 1993 |
| Předmět: |
Hemolytic anemia
Adult Male medicine.medical_specialty Blood transfusion Adolescent Erythroblasts medicine.medical_treatment Thalassemia hemic and lymphatic diseases Internal medicine medicine Humans Blood Transfusion Erythropoietin Hematology medicine.diagnostic_test business.industry Radioimmunoassay General Medicine Middle Aged medicine.disease Endocrinology Hemoglobinopathy Immunoassay Ferritins Female business medicine.drug |
| Zdroj: | Annals of hematology. 67(4) |
| ISSN: | 0939-5555 |
| Popis: | Serum concentrations of erythropoietin (EPO) were determined by immunoassay in 45 patients with thalassemia intermedia (TI). The mean serum level of EPO was significantly higher in the thalassemic patients than in the controls, but transfused subjects had lower pretransfusional serum concentrations of EPO than untransfused ones. An inverse relationship between the serum values of EPO and total hemoglobin was observed only in the untransfused thalassemic patients. These data suggest that in TI, even a low transfusional regimen may cause a decrease in serum concentration of EPO, independent of the level of total Hb. |
| Databáze: | OpenAIRE |
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