Safety and parents´ acceptance of ultrasound contrast agents in children and adolescents - contrast enhanced voiding urosonography and contrast enhanced ultrasound
| Autor: | Matthias Waginger, Paul C. Krüger, Josefina Seelbach, Diane M. Renz, Hans-Joachim Mentzel |
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| Rok vydání: | 2021 |
| Předmět: |
Parents
medicine.medical_specialty Acoustics and Ultrasonics Adolescent media_common.quotation_subject Sulfur Hexafluoride Contrast Media medicine Contrast (vision) Humans Radiology Nuclear Medicine and imaging Prospective Studies Adverse effect Child media_common Ultrasonography Vesico-Ureteral Reflux Radiological and Ultrasound Technology business.industry Ultrasound Infant Newborn Mean age Rash Telephone survey Vomiting Radiology medicine.symptom business Contrast-enhanced ultrasound |
| Zdroj: | Medical ultrasonography. 24(1) |
| ISSN: | 2066-8643 |
| Popis: | Aims: To evaluate the safety of the contrast enhanced voiding urosonography (ceVUS) and contrast enhanced ultrasound (CEUS) in children and adolescence and to receive data about parents’ acceptance of intravesical and intravenous application of sulfur hexafluoride.Material and methods: In this prospective, single centre study conducted over a 1 year study period, parents of 56 children (f/m=32/24; mean age 3.1 years; range 3 weeks - 15.9 years) with ceVUS and of 30 children (f/m=15/15; mean age 10.5 years; range 2 months - 17.7 years) with CEUS agreed to be included. A standardized telephone survey about the acceptance of the parents during and after the procedure as well as the adverse events (AE) were conducted within three days of the examination.Results: The parents would agree with the use of both ceVUS and CEUS as a diagnostic tool again in 96% (54/56) or 100% (30/30) of the cases, respectively and 92.9% (52/56) would prefer ceVUS to voiding cystourethrography (VCUG). In addition, 83.3% (25/30) would prefer CEUS to CT and 73.3% (22/30) would prefer CEUS to MRI. AE were reported in 3.6% after ceVUS (2/56; skin rash, mild fever) and in 3.3% after CEUS (1/30; vomiting). AE were subacute and self‑limited.Conclusions: The vast majority of parents prefer ceVUS and CEUS to VCUG, CT or MRI because of the safety profile of the contrast agent and diagnostic accuracy. |
| Databáze: | OpenAIRE |
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