Placental pathology in smoking and non-smoking preeclamptic women
| Autor: | Sara Falkare, Marie Therese Vinnars, Josefine Nasiell, Nikos Papadogiannakis |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Placenta Diseases Placenta Infarction Preeclampsia Cohort Studies Young Adult 03 medical and health sciences Maternity care 0302 clinical medicine Pre-Eclampsia Pregnancy Placental pathology Humans Medicine 030212 general & internal medicine Abruptio Placentae Gynecology 030219 obstetrics & reproductive medicine Placental abruption business.industry Obstetrics Smoking Infant Newborn Placental tissue Obstetrics and Gynecology medicine.disease Pregnancy Complications medicine.anatomical_structure embryonic structures Pediatrics Perinatology and Child Health Cohort Female business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 29:733-736 |
| ISSN: | 1476-4954 1476-7058 2000-2009 |
| Popis: | To ascertain whether the protective effect of smoking during preeclampsia (PE) can be visualized in the placenta.The study cohort consisted of placentas (n = 523) from pregnancies complicated by PE, delivered at Karolinska University Hospital in Stockholm during the period 2000-2009. Of the women included in the study, 488 were non-smokers and 35 were smokers at first visit to maternity care. Outcome variables were placental infarctions and decidual arteriopathy.Infarctions (affecting ≥5% of the placental tissue) were found in 15.6% of the placentas from non-smokers and in 25.7% of the placentas from smokers (OR 1.88: CI 0.84-4.16, p = 0.12). Decidual arteriopathy was found in 27.5% of the placentas from non-smokers and in 40.0% of the placentas from smokers (1.76: CI 0.87-3.56, p = 0.12). When diagnosed histopathologically, placental abruption was found in 15.4% among non-smokers and in 17.1% among smokers (1.14: CI 0.46-2.84, p = 0.98). Those differences did not show any statistical significance.No significant differences concerning placental infarctions, decidual arteriopathy or abruption were found between preeclamptic placentas from non-smokers compared to smokers. |
| Databáze: | OpenAIRE |
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