Cooperative ligand binding by ferrihemoglobin: An experimental artifact?

Autor:	Alphonso C. I. Anusiem, John G. Beetlestone
Rok vydání:	1976
Předmět:	Artifact (error) Stereochemistry Chemistry Spectrum Analysis Organic Chemistry Temperature Biophysics General Medicine Structural perturbation Hydrogen-Ion Concentration Ligands Biochemistry Methemoglobin Biomaterials sense organs skin and connective tissue diseases Protein Binding
Zdroj:	Biopolymers. 15:403-414
ISSN:	1097-0282 0006-3525
Popis:	We have carried out a detailed study of ligand binding of ferrihemoglobins under various conditions. Our results show that n varies with time and that this variation is paralleled by changes in the spectrum of methemoglobin. This suggests some form of structural perturbation. The time-dependent value of n is discussed in terms of the observed spectral changes accompanying prolonged equilibration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590d75bfb5f5564b02c1eb9ea0af6d35 https://doi.org/10.1002/bip.1976.360150216 Zobrazit plný text záznamu Plný text