Incremental predictive value of myocardial scintigraphy with 123I-BMIPP in patients with acute myocardial infarction treated with primary percutaneous coronary intervention
| Autor: | Haruo Hirayama, Yoshimi Kinoshita, Akitada Ando, Toyoaki Murohara, Ichiro Nanbu, Makoto Nonokawa, Mamoru Nanasato, Mitsuhiro Yokota, Satoshi Isobe |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Acute coronary syndrome medicine.medical_treatment Myocardial Infarction Risk Assessment Sudden death Japan Risk Factors Internal medicine medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Myocardial infarction Angioplasty Balloon Coronary Thallium Radionuclide Imaging Aged Aged 80 and over Ejection fraction Iodobenzenes business.industry Fatty Acids Electrocardiography in myocardial infarction Percutaneous coronary intervention General Medicine Middle Aged Prognosis medicine.disease Survival Rate Treatment Outcome Conventional PCI Cardiology Female Radiopharmaceuticals business Mace |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 31:1512-1521 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-004-1556-3 |
| Popis: | It is unclear whether 123I-labelled β-methyl iodophenyl pentadecanoic acid (123I-BMIPP) myocardial scintigraphy adds further predictive value for future cardiac events compared with the variables obtained during cardiac catheterisation in patients with acute myocardial infarction (AMI) treated with primary percutaneous coronary intervention (PCI). We therefore investigated whether 123I-BMIPP imaging in patients with AMI treated by primary PCI was useful in predicting future cardiac events. One hundred and fifty-nine patients with AMI who were treated with primary PCI and underwent left ventriculography (LVG) on admission underwent 201Tl and 123I-BMIPP myocardial scintigraphy. Scintigrams were visually classified, and the total defect score (TDS) was calculated. Major adverse cardiac events (MACE) were defined as cardiac death including sudden death, congestive heart failure and recurrence of acute coronary syndrome. Patients were followed up for a mean of 34.5 months (12–63 months). Twenty-six patients had MACE. Kaplan-Meier analysis indicated that patients with the top 50% of 123I-BMIPP TDSs had a significantly higher rate of MACE (P=0.007). Patients with mismatch between 201Tl and 123I-BMIPP images also had significantly more MACE (P=0.02). In the prediction of MACE, the global chi-square value was 5.2 (P=0.001) based on LVEF ( |
| Databáze: | OpenAIRE |
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