Clinical implications of the CKD epidemiology collaboration (CKD-EPI) equation compared with the modification of diet in renal disease (MDRD) study equation for the estimation of renal dysfunction in patients with cardiovascular disease

Autor: Giulia Barbati, Giorgio Faganello, Enrico Franceschini Grisolia, Carmine Mazzone, Finlay A. McAlister, Justin A. Ezekowitz, Giovanni Cioffi, Luigi Tarantini, Andrea Di Lenarda, Giulia Russo
Přispěvatelé: Tarantini, Luigi, Barbati, Giulia, Cioffi, Giovanni, Mcalister, Finlay Aleck, Ezekowitz, Justin Adrian, Mazzone, Carmine, Faganello, Giorgio, Russo, Giulia, Grisolia, Enrico Franceschini, DI LENARDA, Andrea
Rok vydání: 2015
Předmět:
Zdroj: Internal and Emergency Medicine. 10:955-963
ISSN: 1970-9366
1828-0447
DOI: 10.1007/s11739-015-1260-2
Popis: The CKD-EPI equation is more accurate than the MDRD equation in the general population. We performed this study to establish whether chronic kidney disease (CKD) is commonly recognized by clinicians and whether the CKD-EPI equation improves prognosis estimation in patients with chronic cardiovascular disease (CVD). We analyzed data on 12394 CVD patients consecutively examined at the Cardiovascular Center of Trieste (Italy) between November 2009 and October 2013. The outcomes were all-cause death and a composite outcome of death/hospitalization for CV events (D+cvH). CKD-EPI formula reclassified 1786 (14.4 %) patients between KDIGO categories compared to the MDRD: 2.3 % (n = 280) placed in a lower risk and 12.1 % (n = 1506) into a higher risk group. CKD, defined as eGFR-CKD-EPI formula 60 but eGFR-CKD-EPI formula
Databáze: OpenAIRE