The 'original' hepatitis B virus of Eastern chimpanzees (Pan trogrodytes schweinfurthii)
| Autor: | Olobo O. Joseph, J. Opuda-Asibo, Georg Pauli, Fabian H. Leendertz, Marco Kaiser, Lawrence Mugisha, Heinz Ellerbrok |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Cancer Research Hepatitis B virus Pan troglodytes Subspecies medicine.disease_cause Antigen Virology Sequence Homology Nucleic Acid medicine Animals Cluster Analysis Uganda Hepatitis B Antibodies Phylogeny Free ranging biology Plasma samples Primate Diseases virus diseases Sequence Analysis DNA Hepatitis B medicine.disease Hepatitis B Core Antigens digestive system diseases Infectious Diseases DNA Viral biology.protein Female Antibody |
| Zdroj: | Virus research. 155(1) |
| ISSN: | 1872-7492 |
| Popis: | Little is known about Hepatitis B Virus (HBV) infections in chimpanzees. Therefore, we investigated the prevalence of chimpanzee HBV (chHBV) infections in captive, wild born chimpanzees in the sanctuary on Ngamba Island, Uganda and one sample from a wild free ranging chimpanzee. In one third of the plasma samples (32.4%; 12/37) we detected antibodies to Hepatitis B (core) antigen. Amongst those individuals HBV DNA was detected in one captive wild born and the wild chimpanzee. In contrast to the only available earlier described HBV sequence from the subspecies Pan troglodytes schweinfurthii, there was no evidence of recombination with human HBV. Our sequences therefore are likely to present the "original" chHBV from P. t. schweinfurthii. |
| Databáze: | OpenAIRE |
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