Real-Time Chemical Analysis of E-Cigarette Aerosols by Means of Secondary Electrospray Ionization Mass Spectrometry
| Autor: | Thomas Gaisl, Renato Zenobi, César Barrios-Collado, Guillermo Vidal-de-Miguel, Diego García-Gómez, Malcolm Kohler |
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| Přispěvatelé: | University of Zurich, Zenobi, Renato |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Generation process
Spectrometry Mass Electrospray Ionization Nicotine 1503 Catalysis Electrospray ionization Analytical chemistry 610 Medicine & health Electronic Nicotine Delivery Systems Secondary electrospray Mass spectrometry 01 natural sciences complex mixtures Catalysis 03 medical and health sciences Analytical methods Electronic cigarettes 0302 clinical medicine Alkaloids 030212 general & internal medicine Chemical composition Aerosols Chromatography Chemistry 010401 analytical chemistry Organic Chemistry Extractive electrospray ionization General Chemistry respiratory system 0104 chemical sciences Aerosol Flavoring Agents 10178 Clinic for Pneumology 1605 Organic Chemistry |
| Zdroj: | Chemistry-A European Journal, 22 (7) Chemistry (Weinheim an der Bergstrasse Germany) |
| ISSN: | 0947-6539 1521-3765 |
| Popis: | Chemical analysis of aerosols collected from electronic cigarettes (ECs) has shown that these devices produce vapors that contain harmful and potentially harmful compounds. Conventional analytical methods used for the analysis of electronic cigarettes do not reflect the actual composition of the aerosols generated because they usually neglect the changes in the chemical composition that occur during the aerosol generation process and after collection. The aim of this work was to develop and apply a method for the real‐time analysis of electronic cigarette aerosols, based on the secondary electrospray ionization technique coupled to high‐resolution mass spectrometry, by mimicking the “vaping” process. Electronic cigarette aerosols were successfully analyzed and quantitative differences were found between the liquids and aerosols. Thanks to the high sensitivity shown by this method, more than 250 chemical substances were detected in the aerosols, some of them showing a high correlation with the operating power of the electronic cigarettes. The method also allows proper quantification of several chemical components such as alkaloids and flavor compounds. Chemistry - A European Journal, 22 (7) ISSN:0947-6539 ISSN:1521-3765 |
| Databáze: | OpenAIRE |
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