Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983
| Autor: | Jennifer S. Rota, Paul A. Rota, Alan P. Kendal, Teresa R. Wallis, Kuniaki Nerome, M W Harmon |
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| Rok vydání: | 1990 |
| Předmět: |
Quadrivalent Inactivated Influenza Vaccine
Genetics Base Sequence Genes Viral biology Sequence analysis viruses Influenzavirus B Molecular Sequence Data Orthomyxoviridae Hemagglutinin (influenza) biology.organism_classification Biological Evolution Virology H5N1 genetic structure Virus Influenza B virus Antigenic variation biology.protein Amino Acid Sequence Oligonucleotide Probes Antigens Viral |
| Zdroj: | Virology. 175:59-68 |
| ISSN: | 0042-6822 |
| DOI: | 10.1016/0042-6822(90)90186-u |
| Popis: | During 1988-1989 two highly distinct antigenic variants of influenza type B were recognized in hemagglutination-inhibition tests with postinfection ferret serum. These viruses were antigenically related to either B/Victoria/2/87, the most recent reference strain, or B/Yamagata/16/88, a variant that was isolated in Japan in May 1988. All influenza B viruses isolated in the United States during an epidemic in the winter of 1988-1989 were antigenically related to B/Victoria/2/87. However, in several countries in Asia, both B/Victoria/2/87-like viruses and B/Yamagata/16/88-like viruses were isolated. Sequence analysis of the hemagglutinin (HA) genes of several influenza B isolates from 1987 to 1988 indicated that the HA1 domains of the B/Yamagata/16/88-like viruses and B/VI/87-like viruses isolated in 1988 differed by 27 amino acids. Evolutionary relationships based on this sequence data indicated that the B/Yamagata/16/88-like viruses were more closely related to epidemic viruses from 1983 (B/USSR/100/83-like viruses) than to more recent reference strains such as B/Victoria/2/87. All other Asian strains, as well as selected isolates from the United States in 1988, were confirmed by sequence analysis as being genetically related to B/Victoria/2/87. These data provide clear evidence that two parallel evolutionary pathways of influenza type B have existed since at least 1983 and that viruses from each of the separate lineages were isolated from cases of influenza B in 1988. This finding is similar to earlier observations for type A H1N1 and H3N2 influenza viruses. |
| Databáze: | OpenAIRE |
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