A Review of Pharmacotherapies for Substance Abuse

Autor:	Elinore McCance, Thomas R. Kosten
Rok vydání:	1996
Předmět:	Fluoxetine medicine.medical_specialty business.industry Medicine (miscellaneous) Target population Serotonergic medicine.disease Cocaine dependence Ondansetron Substance abuse Psychiatry and Mental health Clinical Psychology Opioid Detoxification medicine business Psychiatry medicine.drug
Zdroj:	The American Journal on Addictions. 5:58-65
ISSN:	1521-0391 1055-0496
Popis:	New pharmacotherapies have been developed for acute withdrawal and maintenance treatments of alcohol and opioid dependence but not for cocaine dependence. Highdose, long-acting benzodiazepines, beta-blockers, and two antiseizure agents-carbamuxepine and valproate-are being used for alcohol withdrawal. For maintenance treatment, opioid antagonists and various serotonergic agents, such as fluoxetine and ondansetron, show promise. For opioid dependence, clonidine-na ltrexone detomyication appears quite cost-effective, and buprenoqhine and LAAM (Ievo-alpha-acetylmethadol)s how promise for both detoxification and maintenance. More work is needed, however, to discover an effective agent for target populations of cocaine abusers.
Databáze:	OpenAIRE
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