Relationship between myocardial counts and patient weight: adjusting the injected activity in myocardial perfusion scans
| Autor: | N R Williams, S. Goyle, Alp Notghi, L. K. Harding, N. B. Smith |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Quality Control Correlation coefficient Body Mass Index Increasing weight Organophosphorus Compounds Humans Medicine Radiology Nuclear Medicine and imaging In patient Radiometry Radionuclide Imaging Prospective cohort study Body surface area Dose-Response Relationship Drug business.industry Myocardium Body Weight Heart Organotechnetium Compounds General Medicine Weight range Injections Intravenous Exercise Test Female Radiopharmaceuticals Nuclear medicine business Body mass index Myocardial perfusion scans |
| Zdroj: | Nuclear Medicine Communications. 24:55-59 |
| ISSN: | 0143-3636 |
| Popis: | It is generally accepted that the quality of myocardial images deteriorates with increasing patient weight. This is attributed to a reduction of counts detected from the myocardium. In this paper we have looked at the count reduction in obese patients and suggest a workable algorithm to increase the injected activity to compensate for this loss of count. In this prospective study, 64 consecutive patients with normal myocardial images were selected to include a weight range of 50-120 kg. The height, weight and gender of patients were noted. Each patient had two studies (total of 128 studies), one at rest and one following stress with adenosine and 20-40 W bicycle exercise. Total myocardial counts were calculated from the back-projected views. The total myocardial counts per MBq of the injected activity were calculated. There was no significant difference in the injected activity and the size of the heart (pixel length of heart) between stress and rest, or gender of the patient. The normalized myocardial counts were not different between men and women, but the counts were slightly, although not significantly, higher ( P=NS) with adenosine and exercise (mean of 243 x 10(3) counts) compared to rest images (229 x 10(3) counts). There was a significant progressive loss of counts in patients with increasing weight, body mass index or body surface area ( P |
| Databáze: | OpenAIRE |
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