Childhood leukaemia and socioeconomic status in England and Wales 1976–2005: evidence of higher incidence in relatively affluent communities persists over time
| Autor: | Michael F. Murphy, Lucy M. Carpenter, M E Kroll, Charles A. Stiller |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Gerontology
Cancer Research Pediatrics medicine.medical_specialty Adolescent Epidemiology affluence Social class Rate ratio deprivation socioeconomic status symbols.namesake childhood leukaemia Risk Factors Residence Characteristics medicine Humans Poisson Distribution Registries Poisson regression Child Letter to the Editor Socioeconomic status Wales Leukemia business.industry Incidence (epidemiology) delayed infection Infant Newborn Infant Censuses Census Confidence interval Childhood leukaemia England Social Class Oncology Child Preschool symbols business Demography |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| Popis: | BACKGROUND: Record-based studies have generally reported association of higher childhood leukaemia incidence with higher socioeconomic status (SES), but recent findings are less consistent. METHODS: We examined records from the National Registry of Childhood Tumours for evidence of this association in England and Wales during 1976-2005. All eligible leukaemia registrations (N=11940) were grouped by year of diagnosis in decades centred on census years 1981, 1991 and 2001 (N=3748, 3922, 4270, respectively). Using data from the census appropriate to the decade, SES for each case was measured by the child-population-weighted quintile of the Carstairs deprivation index of the census ward containing the address at diagnosis. RESULTS: In each decade, the age-standardised leukaemia rate in the poorest quintile was ∼90% of the rate in the most affluent. Using Poisson regression, the age-adjusted rate ratio per quintile decrease in SES was 0.96 (95% confidence interval 0.94-0.98; P |
| Databáze: | OpenAIRE |
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