The medial prefrontal cortex is needed for resolving interference even when there are no changes in task rules and strategies
| Autor: | David M. Smith, Gregory J. Peters |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Matching to sample Computer science media_common.quotation_subject Prefrontal Cortex Mnemonic Interference (genetic) Hippocampus Article Task (project management) Behavioral Neuroscience Memory Conflict resolution Animals Attention Rats Long-Evans 0501 psychology and cognitive sciences 050102 behavioral science & comparative psychology Prefrontal cortex Function (engineering) media_common 05 social sciences Flexibility (personality) Rats Odorants Cues Cognitive psychology |
| Zdroj: | Behav Neurosci |
| ISSN: | 1939-0084 0735-7044 |
| DOI: | 10.1037/bne0000347 |
| Popis: | The prefrontal cortex (PFC) plays a key role in behavioral flexibility, and the ability to resolve conflict from shifting strategies, task rules or attentional demands seems to be a hallmark of PFC function. Conflict also occurs in the domain of memory and the PFC plays an important role in the ability to cope with interference between competing retrieval targets. Previous studies often involved both interference and changes in task demands, which makes it difficult to determine the degree to which mnemonic interference per se engages PFC processing. We trained rats on a continuous matching to sample task in two conditions that varied in terms of the amount of interference present but not the task demands and found that temporary inactivation of the medial PFC caused a greater impairment in the high-interference condition. This result suggests that the PFC plays an important role in resolving interference which can be distinguished from its role in shifting task demands. (PsycINFO Database Record (c) 2020 APA, all rights reserved). |
| Databáze: | OpenAIRE |
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