Fenofibrate Reduces C-Reactive Protein Levels in Hypertriglyceridemic Patients With High Risks for Cardiovascular Diseases
| Autor: | Jun Hwan Cho, Eun Young Kim, Wang-Soo Lee, Cheol Won Hyeon, Jee Eun Kwon, Kwang Je Lee, Yun Joo Min, Young Hwan Choi, Chee Jeong Kim, Tae-Ho Kim, Kyung Joon Kim, Sang Wook Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Fibrate Overweight Fenofibric acid C-reactive protein Internal medicine Internal Medicine Medicine Mass index In patient Lipoprotein Fenofibrate biology business.industry Standard treatment Lipids Endocrinology biology.protein Original Article medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Korean Circulation Journal |
| ISSN: | 1738-5555 1738-5520 |
| Popis: | Background and Objectives: The effects of fenofibrate on C-reactive protein (CRP) are under debate. We investigated the effect of fenofi brate on CRP levels and the variables determining changes. Subjects and Methods: This case-control study enrolled 280 hypertriglyceridemic patients who were managed either with 200 mg of fenofibrate (Fenofibrate group, n=140) or with standard treatment (comparison group, n=140). CRP levels were measured before and after management for 2 months. Results: CRP levels decreased in both the fenofibrate (p=0.003) and comparison (p=0.048) groups. Changes in CRP levels were not sig nificantly different between the two groups (p=0.27) and were negatively associated with baseline CRP levels (r=-0.47, p |
| Databáze: | OpenAIRE |
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