Use of hypnotic drugs among children, adolescents, and young adults in Scandinavia
| Autor: | Anton Pottegård, Ingeborg Hartz, Lotte Rasmussen, Mette Bliddal, Johan Reutfors, Peter Bjødstrup Jensen, Svetlana Skurtveit, Poul Jennum, Rikke Wesselhoeft, Per Damkier |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Adolescent medicine.drug_class medicine.medical_treatment Denmark insomnia utilization melatonin Scandinavian and Nordic Countries Hypnotic drugs hypnotics Hypnotic 03 medical and health sciences Young Adult 0302 clinical medicine Sedating Antihistamines medicine Insomnia Humans Hypnotics and Sedatives Young adult Child Sweden business.industry Norway 030227 psychiatry Psychiatry and Mental health Defined daily dose Pharmaceutical Preparations Child Preschool Early adolescents Antihistamine Female sleep disorders Scandinavia medicine.symptom business 030217 neurology & neurosurgery Demography |
| Zdroj: | Wesselhoeft, R, Rasmussen, L, Jensen, P B, Jennum, P J, Skurtveit, S, Hartz, I, Reutfors, J, Damkier, P, Bliddal, M & Pottegård, A 2021, ' Use of hypnotic drugs among children, adolescents, and young adults in Scandinavia ', Acta Psychiatrica Scandinavica, vol. 144, no. 2, pp. 100-112 . https://doi.org/10.1111/acps.13329 Acta Psychiatrica Scandinavica |
| DOI: | 10.1111/acps.13329 |
| Popis: | Background: Hypnotic use in children and adolescents is controversial. Objective: To describe the use of hypnotic drugs (melatonin, z-drugs, and sedating antihistamines) among 5- to 24-year-old Scandinavians during 2012 to 2018. Methods: Aggregate-level data were obtained from public data sources in Sweden, Norway, and Denmark. We calculated annual prevalence (users/1000 inhabitants) stratified by age group, sex, and country. Quantity of use (Defined Daily Dose (DDD)/user/day) was estimated for Norway and Denmark. Results: Melatonin was the most commonly used hypnotic, and its use increased markedly from 2012 to 2018, particularly among females and 15- to 24-year-old individuals. Sweden had the highest increase in use (6.5 to 25/1000) compared with Norway (10–20/1000) and Denmark (5.7–12/1000). The annual prevalence of sedating antihistamine use was also highest in Sweden, reaching 13/1000 in 2018 in comparison to 7.5/1000 in Norway and 2.5/1000 in Denmark. Z-drug use decreased in all countries toward 2018, dropping to 3.5/1000 in Sweden, 4.4/1000 in Norway, and 1.7/1000 in Denmark. The quantity of hypnotic use in Norway and Denmark was 0.8–1.0 DDD/user/day for melatonin in 2018, as compared to 0.1–0.3 for z-drugs and antihistamines. Conclusion: The use of melatonin and sedating antihistamines increased among young Scandinavians during 2012–2018, and the increase was twice as high in Sweden compared with Norway and Denmark. In addition, Sweden had the highest use of sedating antihistamines. The Scandinavian variation of hypnotic use could reflect differences in frequency of sleep problems between populations or variation of healthcare access or clinical practice between countries. |
| Databáze: | OpenAIRE |
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