Citalopram associated with acute angle-closure glaucoma: case report
| Autor: | Robert Croos, Srinivasa Thirumalai, Sabit Hassan, Jane da Roza Davis |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Intraocular pressure
Pediatrics medicine.medical_specialty genetic structures Visual Acuity Glaucoma Case Report Citalopram Drug overdose lcsh:Ophthalmology Medicine Humans Medical history Depression (differential diagnoses) Intraocular Pressure business.industry General Medicine Middle Aged medicine.disease eye diseases Ophthalmology lcsh:RE1-994 Anesthesia Acute Disease Etiology Antidepressive Agents Second-Generation Female sense organs Drug Overdose business Complication Glaucoma Angle-Closure medicine.drug |
| Zdroj: | BMC Ophthalmology BMC Ophthalmology, Vol 5, Iss 1, p 23 (2005) |
| ISSN: | 1471-2415 |
| Popis: | Background Acute angle-closure glaucoma is a rare complication in patients receiving anti-depressant treatment. In the following case, we report the development of acute angle closure glaucoma in a patient who overdosed on Citalopram, an antidepressant, and discuss the possible etiological mechanisms for the condition. Case presentation We report a 54 year old, Caucasian lady, with depression and alcohol dependence syndrome, who developed acute angle-closure glaucoma after an overdose of Citalopram, along with alcohol. She was treated with medications and had bilateral Yag laser iridotomies to correct the glaucoma and has made complete recovery. In this case, the underlying cause for glaucoma appears to be related to the ingestion of Citalopram. Conclusion The patho-physiological basis for acute angle closure glaucoma in relation to antidepressant medications remains unclear. The authors suggest Citalopram may have a direct action on the Iris or Ciliary body muscle through serotonergic or anti-cholinergic mechanisms or both. This case highlights the importance of the awareness of the underlying risks, which may predispose an individual to develop acute angle-closure glaucoma, and reminds the clinicians the significance of history taking and examination of the eye before and after starting anti-depressants. This area needs to be further researched. |
| Databáze: | OpenAIRE |
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