Quantifying upper limb tremor in people with multiple sclerosis using Fast Fourier Transform based analysis of wrist accelerometer signals
| Autor: | Ben Stansfield, Jenny Preston, Frederike van Wijck, Stefan Teufl |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty business.industry Multiple sclerosis Fast Fourier transform Disease progression algorithm development Wrist medicine.disease Accelerometer tremor nervous system diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Physical medicine and rehabilitation wrist accelerometer sensor medicine Upper limb Original Article 0305 other medical science business 030217 neurology & neurosurgery Fast Fourier Transform analysis |
| Zdroj: | Journal of Rehabilitation and Assistive Technologies Engineering |
| ISSN: | 2055-6683 |
| DOI: | 10.1177/2055668320966955 |
| Popis: | Introduction Tremor is a disabling symptom of Multiple Sclerosis (MS). The development of objective methods of tremor characterisation to assess intervention efficacy and disease progression is therefore important. The possibility of using a Fast Fourier Transform (FFT) method for tremor detection was explored. Methods Acceleration from a wrist-worn device was analysed using FFTs to identify and characterise tremor magnitude and frequency. Processing parameters were explored to provide insight into the optimal algorithm. Participants wore a wrist tri-axial accelerometer during 9 tasks. The FAHN clinical assessment of tremor was used as the reference standard. Results Five people with MS and tremor (57.6 ± 15.3 years, 3 F/2M) and ten disease-free controls (42.4 ± 10.9 years, 5 M/5F) took part. Using specific algorithm settings tremor identification was possible (peak frequency 3–15Hz; magnitude greater than 0.06 g; 2 s windows with 50% overlap; using 2 of 3 axes of acceleration), giving sensitivity 0.974 and specificity 0.971 (38 tremor occurrences out of 108 tasks, 1 false positive, 2 false negatives). Tremor had frequency 3.5–13.0 Hz and amplitude 0.07–2.60g. Conclusions Upper limb tremor in people with MS can be detected using a FFT approach based on acceleration recorded at the wrist, demonstrating the possibility of using this minimally encumbering technique within clinical practice. |
| Databáze: | OpenAIRE |
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