Co-existent Addison's disease and thyrotoxicosis

Autor: Ober Wb, Jeanne A. Epstein, Michael S. Bruno, Herbert S. Kupperman
Rok vydání: 1962
Předmět:
Zdroj: Archives of internal medicine. 110
ISSN: 0003-9926
Popis: The coexistence of Addison's disease and thyrotoxicosis in the same individual is a medical rarity. Critical review of the literature reveals only 12 adequately documented instances1-11of this association. Chronologic study of these cases mirrors the steady increase in our understanding of endocrine diseases at the bedside and the development of newer techniques in the laboratory. The first 4 reported cases1-4were all rapidly fatal, and the diagnosis of adrenocortical atrophy and thyroid hyperplasia was made at autopsy in 3 of them.1,3,4The first successfully treated case was reported by Perera and Parker.5All subsequently reported cases were treated successfully except for one of the 2 adequately documented cases reported by Houston and Price (Case 3).6Two patients4,8had developed diabetes mellitus less than 5 years before the onset of thyrotoxicosis; they developed Addison's disease subsequently. Another patient11developed mild thyrotoxicosis 3
Databáze: OpenAIRE