Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria
| Autor: | Heidi Snyman, Benjamin Prud'homme, Gáspár Jékely, Alexandru S. Denes, Patrick R. H. Steinmetz, David E. K. Ferrier, Florian Raible, Detlev Arendt, Guillaume Balavoine |
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| Přispěvatelé: | Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), European Molecular Biology Laboratory [Heidelberg] (EMBL), Departement of Zoology, University of Oxford, University of Oxford [Oxford], Centre de génétique moléculaire (CGM), Centre National de la Recherche Scientifique (CNRS), University of Oxford |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Nervous system
Central Nervous System MESH: Bone Morphogenetic Proteins MESH: Neurons DEVBIO EVO ECOL MESH: Gene Expression Regulation Developmental Paired Box Transcription Factors MESH: Animals Bilateria MESH: Vertebrates Neurons 0303 health sciences [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] 030302 biochemistry & molecular biology Pax genes Gene Expression Regulation Developmental Anatomy MESH: Transcription Factors Biological Evolution medicine.anatomical_structure Bone Morphogenetic Proteins Vertebrates Platynereis MESH: Body Patterning Evolution of nervous systems animal structures MESH: Polychaeta [SDV.BC]Life Sciences [q-bio]/Cellular Biology Biology MOLNEURO General Biochemistry Genetics and Molecular Biology 03 medical and health sciences MESH: Evolution MESH: Homeodomain Proteins medicine Animals MESH: Central Nervous System [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology Spiralia MESH: Paired Box Transcription Factors 030304 developmental biology Body Patterning Homeodomain Proteins Neuroectoderm Biochemistry Genetics and Molecular Biology(all) Neural tube Polychaeta biology.organism_classification [SDV.BDD.EO]Life Sciences [q-bio]/Development Biology/Embryology and Organogenesis Evolutionary biology CELLBIO Transcription Factors |
| Zdroj: | Cell Cell, 2007, 129 (2), pp.277-288 Cell, Elsevier, 2007, 129 (2), pp.277-88. ⟨10.1016/j.cell.2007.02.040⟩ Cell, Elsevier, 2007, 129 (2), pp.277-288 Cell, 2007, 129 (2), pp.277-88. ⟨10.1016/j.cell.2007.02.040⟩ |
| ISSN: | 0092-8674 1097-4172 |
| DOI: | 10.1016/j.cell.2007.02.040⟩ |
| Popis: | SummaryTo elucidate the evolutionary origin of nervous system centralization, we investigated the molecular architecture of the trunk nervous system in the annelid Platynereis dumerilii. Annelids belong to Bilateria, an evolutionary lineage of bilateral animals that also includes vertebrates and insects. Comparing nervous system development in annelids to that of other bilaterians could provide valuable information about the common ancestor of all Bilateria. We find that the Platynereis neuroectoderm is subdivided into longitudinal progenitor domains by partially overlapping expression regions of nk and pax genes. These domains match corresponding domains in the vertebrate neural tube and give rise to conserved neural cell types. As in vertebrates, neural patterning genes are sensitive to Bmp signaling. Our data indicate that this mediolateral architecture was present in the last common bilaterian ancestor and thus support a common origin of nervous system centralization in Bilateria. |
| Databáze: | OpenAIRE |
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