Supplementation with babassu oil reduces fatigue and inflammation in breast cancer patients: A pilot randomized clinical trial
| Autor: | Monica Virginia Viegas Lima-Aragão, João Batista Santos Garcia, Flávia R.F. Nascimento, Mayara Cristina Pinto Silva, Rosane N. M. Guerra, Richard Diego Leite, Larissa de Lourdes Padilha Serra, Andréa Dias Reis, Paula Tâmara Vieira Teixeira Pereira, Surama Do Carmo Sousa Da Silva |
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| Přispěvatelé: | Universidade Federal do Maranhão – Centro de Ciências Biológicas e da Saúde, Pain and Palliative Care – Centro de Ciências Biológicas e da Saúde, Universidade Estadual Paulista (Unesp), Universidade Federal do Espírito Santo (UFES) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Saliva food.ingredient Medicine (miscellaneous) Inflammation Gastroenterology Proinflammatory cytokine law.invention Immunomodulation 03 medical and health sciences 0404 agricultural biotechnology Breast cancer food Quality of life Randomized controlled trial law Internal medicine medicine TX341-641 Fatigue 030109 nutrition & dietetics Nutrition and Dietetics business.industry Nutrition. Foods and food supply Coconut oil 04 agricultural and veterinary sciences medicine.disease Dietary supplements 040401 food science Babassu oil medicine.symptom business Food Science |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Journal of Functional Foods, Vol 73, Iss, Pp 104105-(2020) |
| Popis: | Made available in DSpace on 2020-12-12T01:33:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-01 Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão This study investigated the effects of babassu and coconut oil supplementation in breast cancer patients. This randomized clinical trial included 60 patients divided into three groups: untreated control group (CG), babassu oil group (BG), and coconut oil group (COG). Fatigue, quality of life, depression, tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and salivary IgA were analysed before and after 12 weeks of supplementation. Babassu supplementation decreased fatigue and improved quality of life but did not affect depression scores. Babassu also decreased TNF-α and IL-6 levels and increased IgA in saliva compared to the COG and CG. In conclusion, babassu oil supplementation reduced fatigue and improved the quality of life of breast cancer patients, and these outcomes are probably related to the immunomodulatory effects of babassu oil in reducing proinflammatory cytokines and increasing IgA antibody production. These findings indicate that babassu oil may be useful as a supplement to reduce cancer-related fatigue. Laboratory of Immunophysiology Universidade Federal do Maranhão – Centro de Ciências Biológicas e da Saúde Pain and Palliative Care – Centro de Ciências Biológicas e da Saúde Universidade Estadual Paulista - UNESP Universidade Federal do Espírito Santo Universidade Estadual Paulista - UNESP |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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