Eosinophilia in infants with food protein-induced enterocolitis syndrome in Japan
| Autor: | Shiro Seto, Masaki Shimomura, Takaaki Meguro, Hideaki Morishita, Mitsuaki Kimura |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
lcsh:Immunologic diseases. Allergy Proctocolitis medicine.medical_specialty Gastroenterology 03 medical and health sciences 0302 clinical medicine Japan Food protein-induced enterocolitis syndrome 030225 pediatrics Internal medicine Eosinophilia Humans Immunology and Allergy Medicine Age of Onset Enterocolitis business.industry Incidence Incidence (epidemiology) Infant Newborn Infant Syndrome General Medicine medicine.disease Bloody Diarrhea Phenotype 030228 respiratory system Immunology Vomiting Cytokines Female Interleukin-5 medicine.symptom Food protein-induced proctocolitis lcsh:RC581-607 business Infants Food Hypersensitivity |
| Zdroj: | Allergology International, Vol 66, Iss 2, Pp 310-316 (2017) |
| ISSN: | 1323-8930 |
| Popis: | Background: Many Japanese infants with food protein-induced enterocolitis syndrome (FPIES) show eosinophilia, which has been thought to be a characteristic of food protein-induced proctocolitis (FPIP). Methods: To elucidate the characteristics of eosinophilia in Japanese FPIES patients, 113 infants with non-IgE-mediated gastrointestinal food allergy due to cow's milk were enrolled and classified into FPIES (n = 94) and FPIP (n = 19). Results: The percentage of peripheral blood eosinophils (Eo) was increased in most FPIES patients (median, 7.5%), which was comparable with that in FPIP patients (9.0%). Among FPIES patients, Eo was the highest in patients who had vomiting, bloody stool, and diarrhea simultaneously (12.9%) and lowest in patients with diarrhea alone (3.2%). Eo showed a significant positive correlation with the incidence of vomiting (Cramer's V = 0.31, p 10 days, n = 38) FPIES (median, 9.8% vs. 5.4%; p |
| Databáze: | OpenAIRE |
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