| Autor: |
Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Tables S1-S15. Table S1. Genes and positions analyzed by amplicon sequencing. Table S2. Genes sequenced by Haloplex Target Enrichment System. Table S3. Antibodies. Table S4. Treatment-induced apoptosis in 10 primary patient-derived sphere cell cultures. Table S5. Genotype of patient-derived colorectal cancer models. Table S6. Exome sequencing of colorectal cancer patient-derived models. Table S7. Genes regulated by NVP-TNKS656 in PDX-P2. Table S8. Genes regulated by NVP-TNKS656 in PDX-P30. Table S9. Genes regulated by NVP-TNKS656 in PDX-P5. Table S10. Intestinal β-catenin/TCF signature in human CRC. Table S11. Genes regulated by β-catenin/FOXO3A signaling in human CRC. Table S12. Molecular profiling of 130 CRC tumors. Table S13. Clinicopathological data of 40 CRC patients treated with PI3K/AKT/mTOR inhibitors and their corresponding baseline tumor samples analyzed for mutations and nuclear β-catenin content. Table S14. Nuclear β-catenin content but not relevant mutations or TNM stage determine response of CRC patients to PI3K/AKT/mTOR inhibitors. Table S15. Multivariate analysis of baseline tumors from patients treated with PI3K/AKT/mTOR inhibitors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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